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Could Pharma Use a Dose of Paranoid Leadership?


I took time this morning to listen to a podcast interview with MIT Sloan professor Steven Spear on what characterizes “high velocity” organizations. (Spear is the author of “Chasing the Rabbit: How Market Leaders Outdistance the Competition,” and a new book called "The High-Velocity Edge".) Such organizations, Spear says, are able to effect dramatic improvements within extremely short windows of time.

From 'On Pharma'

Pharma CEOs' Big Question - Should I Stay Or Should I Go?


A growing number of pharma CEOs are now dealing with the consequences of failing to care about workplace realities and what Toyota called the gemba, or place where truth will be found.

If the idea of reading a book on ethics or philosophy is too off-putting....after all, it has been a rough week....why not simply listen to The Clash's hit song "Should I Stay or Should I Go?" The answer's right there. "If I go there will be trouble, and if I stay it will be double."  
From 'On Pharma'

EZ Pass Testing, Coercion and Buck Passing: A Tale of Broken Pharma QA and QC. Sound Familiar?


Just read Mina Kimes' enlightening account of the J&J McNeil quality disaster in Fortune. Forget about the fact that the adulterated products did not and most likely would not have harmed consumers, the problems cited are very serious and go straight to the heart of GMP's.

From 'On Pharma'

Can Lean Negate Quality Control? Lessons From Fallen Lean Icons Toyota and J&J


Recent postings in the WSJ blog and elsewhere have asked the troubling question: Does Lean Manufacturing, by definition, lead to quality control problems? Click here for an interesting read. (For something that doesn't require registration, click here.)

From 'On Pharma'

Go Out and Gemba


I've always found one of the most evocative terms in the Toyota lexicon to be “gemba” ----the real place, or as it has more poetically been translated, “the place where truth will be found.”  The word already implies that you may have preconceived notions of what the truth is and need a reality check. What better way to define the workplace, whether that's a laboratory or a factory?

From 'On Pharma'

Toyota to Close NUMMI Plant in Fremont


In a sad turning point in Toyota's history, and, perhaps the whole history of the Lean movement, Toyota  plans to liquidate the Lean showcase NUMMI plant in Fremont, California "by the end of August." Read more from yesterday's story in the San Francisco Business News.

From 'On Pharma'

Toyota NUMMI: Optimism at the dawn of a new era?


Last month, I visited a Toyota plant for the first time, the fabled NUMMI plant in Fremont, California.  The factory has fallen on harder times:  production stopped on some lines in December.  

From 'On Pharma'